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The CD47-binding peptide of thrombospondin-1 induces defenestration of liver sinusoidal endothelial cells

BACKGROUND & AIMS: A fenestrated phenotype is characteristic of liver sinusoidal endothelial cells (LSECs), but liver sinusoids become defenestrated during fibrosis and other liver diseases. Thrombospondin-1 (TSP1) is a matrix glycoprotein with pro-fibrotic effects, and the CD47-binding fragment...

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Detalles Bibliográficos
Autores principales:	Venkatraman, Lakshmi, Tucker-Kellogg, Lisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2013
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285809/ https://www.ncbi.nlm.nih.gov/pubmed/23799952 http://dx.doi.org/10.1111/liv.12231

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