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Effects of Ranolazine on Torsades de Pointes Tachycardias in a Healthy Isolated Rabbit Heart Model

PURPOSE: Torsades de pointes (TdP) tachycardias are triggered, polymorphic ventricular arrhythmias arising from early afterdepolarizations (EADs) and increased dispersion of repolarization. Ranolazine is a new agent which reduces pathologically elevated late I(Na) but also I(Kr). Aim of this study w...

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Detalles Bibliográficos
Autores principales:	Sossalla, Samuel, Wallisch, Nora, Toischer, Karl, Sohns, Christian, Vollmann, Dirk, Seegers, Joachim, Lüthje, Lars, Maier, Lars S, Zabel, Markus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Original Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285941/ https://www.ncbi.nlm.nih.gov/pubmed/24785406 http://dx.doi.org/10.1111/1755-5922.12078

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