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Enforced telomere elongation increases the sensitivity of human tumour cells to ionizing radiation
More than 85% of all human cancers possess the ability to maintain chromosome ends, or telomeres, by virtue of telomerase activity. Loss of functional telomeres is incompatible with survival, and telomerase inhibition has been established in several model systems to be a tractable target for cancer...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286114/ https://www.ncbi.nlm.nih.gov/pubmed/25484304 http://dx.doi.org/10.1016/j.dnarep.2014.11.005 |