Alternative splicing of TIA‐1 in human colon cancer regulates VEGF isoform expression, angiogenesis, tumour growth and bevacizumab resistance

The angiogenic capability of colorectal carcinomas (CRC), and their susceptibility to anti‐angiogenic therapy, is determined by expression of vascular endothelial growth factor (VEGF) isoforms. The intracellular protein T‐cell Intracellular Antigen (TIA‐1) alters post‐transcriptional RNA processing...

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Detalles Bibliográficos
Autores principales: Hamdollah Zadeh, Maryam A., Amin, Elianna M., Hoareau-Aveilla, Coralie, Domingo, Enric, Symonds, Kirsty E., Ye, Xi, Heesom, Katherine J., Salmon, Andrew, D'Silva, Olivia, Betteridge, Kai B., Williams, Ann C., Kerr, David J., Salmon, Andrew H.J., Oltean, Sebastian, Midgley, Rachel S., Ladomery, Michael R., Harper, Steven J., Varey, Alexander H.R., Bates, David O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286123/
https://www.ncbi.nlm.nih.gov/pubmed/25224594
http://dx.doi.org/10.1016/j.molonc.2014.07.017

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