Cargando…

A tumor DNA complex aberration index is an independent predictor of survival in breast and ovarian cancer

Complex focal chromosomal rearrangements in cancer genomes, also called “firestorms”, can be scored from DNA copy number data. The complex arm‐wise aberration index (CAAI) is a score that captures DNA copy number alterations that appear as focal complex events in tumors, and has potential prognostic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vollan, Hans Kristian Moen, Rueda, Oscar M., Chin, Suet-Feung, Curtis, Christina, Turashvili, Gulisa, Shah, Sohrab, Lingjærde, Ole Christian, Yuan, Yinyin, Ng, Charlotte K., Dunning, Mark J., Dicks, Ed, Provenzano, Elena, Sammut, Stephen, McKinney, Steven, Ellis, Ian O., Pinder, Sarah, Purushotham, Arnie, Murphy, Leigh C., Kristensen, Vessela N., Brenton, James D., Pharoah, Paul D.P., Børresen-Dale, Anne-Lise, Aparicio, Samuel, Caldas, Carlos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2014
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286124/ https://www.ncbi.nlm.nih.gov/pubmed/25169931 http://dx.doi.org/10.1016/j.molonc.2014.07.019

Ejemplares similares

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
por: Curtis, Christina, et al.
Publicado: (2012)

The somatic mutation profiles of 2,433 breast cancers refines their genomic and transcriptomic landscapes
por: Pereira, Bernard, et al.
Publicado: (2016)

Erratum: The somatic mutation profiles of 2,433 breast cancers refine their genomic and transcriptomic landscapes
por: Pereira, Bernard, et al.
Publicado: (2016)

Copynumber: Efficient algorithms for single- and multi-track copy number segmentation
por: Nilsen, Gro, et al.
Publicado: (2012)

Dynamics of breast cancer relapse reveal late recurring ER-positive genomic subgroups
por: Rueda, Oscar M., et al.
Publicado: (2019)

Integrative analysis of genome-wide loss of heterozygosity and monoallelic expression at nucleotide resolution reveals disrupted pathways in triple-negative breast cancer
por: Ha, Gavin, et al.
Publicado: (2012)

Associations between genomic stratification of breast cancer and centrally reviewed tumour pathology in the METABRIC cohort
por: Mukherjee, A., et al.
Publicado: (2018)

Systematic assessment of prognostic gene signatures for breast cancer shows distinct influence of time and ER status
por: Zhao, Xi, et al.
Publicado: (2014)

ADNP (Activity Dependent Neuroprotector Homeobox): A novel oncogene driving poor prognosis in high-grade serous carcinoma
por: Turashvili, Gulisa
Publicado: (2020)

Genome-driven integrated classification of breast cancer validated in over 7,500 samples
por: Ali, H Raza, et al.
Publicado: (2014)

DNA methylation landscapes of 1538 breast cancers reveal a replication-linked clock, epigenomic instability and cis-regulation
por: Batra, Rajbir Nath, et al.
Publicado: (2021)

Tumor Heterogeneity in Breast Cancer
por: Turashvili, Gulisa, et al.
Publicado: (2017)

Pathology of Hereditary Breast and Ovarian Cancer
por: Hodgson, Anjelica, et al.
Publicado: (2020)

What’s new in gynecologic pathology 2021: ovary and fallopian tube
por: Turashvili, Gulisa, et al.
Publicado: (2021)

Are Columnar Cell Lesions the Earliest Non-Obligate Precursor in the Low-Grade Breast Neoplasia Pathway?
por: Strickland, Sarah, et al.
Publicado: (2022)

Tumor expression, plasma levels and genetic polymorphisms of the coagulation inhibitor TFPI are associated with clinicopathological parameters and survival in breast cancer, in contrast to the coagulation initiator TF
por: Tinholt, Mari, et al.
Publicado: (2015)

The breast cancer genome - a key for better oncology
por: Vollan, Hans Kristian Moen, et al.
Publicado: (2011)

Calling Sample Mix-Ups in Cancer Population Studies
por: Lynch, Andy G., et al.
Publicado: (2012)

The pitfalls of platform comparison: DNA copy number array technologies assessed
por: Curtis, Christina, et al.
Publicado: (2009)

Editorial: Hereditary Breast and Ovarian Cancer: Current Concepts of Prevention and Treatment
por: Grabenstetter, Anne, et al.
Publicado: (2020)

Intersect-then-combine approach: improving the performance of somatic variant calling in whole exome sequencing data using multiple aligners and callers
por: Callari, Maurizio, et al.
Publicado: (2017)

Data-driven analysis of immune infiltrate in a large cohort of breast cancer and its association with disease progression, ER activity, and genomic complexity
por: Dannenfelser, Ruth, et al.
Publicado: (2017)

Mll5 Is Required for Normal Spermatogenesis
por: Yap, Damian B., et al.
Publicado: (2011)

Integrated analysis reveals microRNA networks coordinately expressed with key proteins in breast cancer
por: Aure, Miriam Ragle, et al.
Publicado: (2015)

JointSNVMix: a probabilistic model for accurate detection of somatic mutations in normal/tumour paired next-generation sequencing data
por: Roth, Andrew, et al.
Publicado: (2012)

Inter-observer reproducibility of HER2 immunohistochemical assessment and concordance with fluorescent in situ hybridization (FISH): pathologist assessment compared to quantitative image analysis
por: Turashvili, Gulisa, et al.
Publicado: (2009)

Breast tumor microenvironment structures are associated with genomic features and clinical outcome
por: Danenberg, Esther, et al.
Publicado: (2022)

Linear and non-linear dependencies between copy number aberrations and mRNA expression reveal distinct molecular pathways in breast cancer
por: Solvang, Hiroko K, et al.
Publicado: (2011)

The testosterone-dependent and independent transcriptional networks in the hypothalamus of Gpr54 and Kiss1 knockout male mice are not fully equivalent
por: Prentice, Leah M, et al.
Publicado: (2011)

Shallow whole genome sequencing for robust copy number profiling of formalin-fixed paraffin-embedded breast cancers
por: Chin, Suet-Feung, et al.
Publicado: (2018)

Report on the 1st Indian Cancer Congress 2013
por: Sullivan, Richard, et al.
Publicado: (2013)

PMC42, a breast progenitor cancer cell line, has normal-like mRNA and microRNA transcriptomes
por: Git, Anna, et al.
Publicado: (2008)

Computational approach to discriminate human and mouse sequences in patient-derived tumour xenografts
por: Callari, Maurizio, et al.
Publicado: (2018)

Multi-omic machine learning predictor of breast cancer therapy response
por: Sammut, Stephen-John, et al.
Publicado: (2021)

Decline in Antigenicity of Tumor Markers by Storage Time Using Pathology Sections Cut From Tissue Microarrays
por: Blows, Fiona M., et al.
Publicado: (2016)

ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium
por: Holland, Daniel G, et al.
Publicado: (2011)

Time series analysis of neoadjuvant chemotherapy and bevacizumab-treated breast carcinomas reveals a systemic shift in genomic aberrations
por: Höglander, Elen Kristine, et al.
Publicado: (2018)

Prognostic Value of MammaPrint(®) in Invasive Lobular Breast Cancer
por: Beumer, Inès J., et al.
Publicado: (2016)

Breast carcinoma with 21-gene recurrence score lower than 18: rate of locoregional recurrence in a large series with clinical follow-up
por: Turashvili, Gulisa, et al.
Publicado: (2018)

Brain metastasis in advanced serous borderline tumor of the ovary: A case presentation()
por: Martin, Madhuri, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_hf5kllb08einh2qke7a6fhasdo