The clinically approved drugs dasatinib and bosutinib induce anti-inflammatory macrophages by inhibiting the salt-inducible kinases

Macrophages switch to an anti-inflammatory, ‘regulatory’-like phenotype characterized by the production of high levels of interleukin (IL)-10 and low levels of pro-inflammatory cytokines to promote the resolution of inflammation. A potential therapeutic strategy for the treatment of chronic inflamma...

Descripción completa

Detalles Bibliográficos
Autores principales: Ozanne, James, Prescott, Alan R., Clark, Kristopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286194/
https://www.ncbi.nlm.nih.gov/pubmed/25351958
http://dx.doi.org/10.1042/BJ20141165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286194/
https://www.ncbi.nlm.nih.gov/pubmed/25351958
http://dx.doi.org/10.1042/BJ20141165

Ejemplares similares