Nanoscale stiffness topography reveals structure and mechanics of the transport barrier in intact nuclear pore complexes

The nuclear pore complex (NPC) is the gate for transport between the cell nucleus and the cytoplasm. Small molecules cross the NPC by passive diffusion, but molecules larger than ~5 nm must bind to nuclear transport receptors to overcome a selective barrier within the NPC(1). Whilst the structure an...

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Detalles Bibliográficos
Autores principales: Bestembayeva, Aizhan, Kramer, Armin, Labokha, Aksana A., Osmanović, Dino, Liashkovich, Ivan, Orlova, Elena V., Ford, Ian J., Charras, Guillaume, Fassati, Ariberto, Hoogenboom, Bart W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286247/
https://www.ncbi.nlm.nih.gov/pubmed/25420031
http://dx.doi.org/10.1038/nnano.2014.262

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