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Carnitine Palmitoyltransferase 1b Deficient Mice Develop Severe Insulin Resistance After Prolonged High Fat Diet Feeding

BACKGROUND: Carnitine palmitoyltransferase 1 (CPT1) is the rate-limiting enzyme governing the entry of long-chain acyl-CoAs into mitochondria. Treatments with CPT1 inhibitors protect against insulin resistance in short-term preclinical animal studies. We recently reported that mice with muscle isofo...

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Detalles Bibliográficos
Autores principales:	Kim, Teayoun, Moore, John F, Sharer, Jon D, Yang, Kevin, Wood, Philip A, Yang, Qinglin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286342/ https://www.ncbi.nlm.nih.gov/pubmed/25580367 http://dx.doi.org/10.4172/2155-6156.1000401

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