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Resveratrol induces apoptosis by directly targeting Ras-GTPase activating protein SH3 domain binding protein 1 (G3BP1)
Resveratrol possesses a strong anticancer activity exhibited as the induction of apoptosis through p53 activation. However, the molecular mechanism and direct target(s) of resveratrol-induced p53 activation remain elusive. Here, the Ras-GTPase activating protein SH3 domain binding protein 1 (G3BP1)...
Autores principales: | Oi, Naomi, Yuan, Jian, Malakhova, Margarita, Luo, Kuntian, Li, Yunhui, Ryu, Joohyun, Zhang, Lei, Bode, Ann M., Xu, Zengguang, Li, Yan, Lou, Zhenkun, Dong, Zigang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286533/ https://www.ncbi.nlm.nih.gov/pubmed/24998844 http://dx.doi.org/10.1038/onc.2014.194 |
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