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TCR and CD28 activate the transcription factor NF-κB in T-cells via distinct adaptor signaling complexes
The transcription factor NF-κB is needed for the induction of inflammatory responses in T-cells. Whether its activation by the antigen-receptor and CD28 is mediated by the same or different intracellular signaling pathways has been unclear. Here, using T-cells from various knock-out (Cd28(−/−), adap...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier/North-Holland Biomedical Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286576/ https://www.ncbi.nlm.nih.gov/pubmed/25455592 http://dx.doi.org/10.1016/j.imlet.2014.10.020 |