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The homeodomain of Eyeless regulates cell growth and antagonizes the paired domain-dependent retinal differentiation function
Pax6 and its Drosophila homolog Eyeless (Ey) play essential roles during eye development. Ey/Pax6 contains two distinct DNA binding domains, a Paired domain (PD) and a Homeodomain (HD). While Ey/Pax6 PD is required for the expression of key regulators of retinal development, relatively little is kno...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Higher Education Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286722/ https://www.ncbi.nlm.nih.gov/pubmed/25234589 http://dx.doi.org/10.1007/s13238-014-0101-9 |