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The Effects of Bronchoscope Diameter on the Diagnostic Yield of Transbronchial Lung Biopsy of Peripheral Pulmonary Nodules

BACKGROUND: Transbronchial lung biopsy (TBLB) is a valuable diagnostic tool for peripheral pulmonary lesions. The diagnostic yield of TBLB reportedly ranges from 41%-60%. Many studies demonstrated the various factors that influence the yield of TBLB, including size, location, and distance from the c...

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Autores principales: Lee, Nakwon, Kim, Sang-Ha, Kwon, Woocheol, Lee, Myoung Kyu, Yong, Suk Joong, Shin, Kye Chul, Jung, Ye-Ryung, Choi, Yeun Seoung, Choi, Jiwon, Choi, Ji Sun, Lee, Won Yeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Tuberculosis and Respiratory Diseases 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286782/
https://www.ncbi.nlm.nih.gov/pubmed/25580141
http://dx.doi.org/10.4046/trd.2014.77.6.251
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author Lee, Nakwon
Kim, Sang-Ha
Kwon, Woocheol
Lee, Myoung Kyu
Yong, Suk Joong
Shin, Kye Chul
Jung, Ye-Ryung
Choi, Yeun Seoung
Choi, Jiwon
Choi, Ji Sun
Lee, Won Yeon
author_facet Lee, Nakwon
Kim, Sang-Ha
Kwon, Woocheol
Lee, Myoung Kyu
Yong, Suk Joong
Shin, Kye Chul
Jung, Ye-Ryung
Choi, Yeun Seoung
Choi, Jiwon
Choi, Ji Sun
Lee, Won Yeon
author_sort Lee, Nakwon
collection PubMed
description BACKGROUND: Transbronchial lung biopsy (TBLB) is a valuable diagnostic tool for peripheral pulmonary lesions. The diagnostic yield of TBLB reportedly ranges from 41%-60%. Many studies demonstrated the various factors that influence the yield of TBLB, including size, location, and distance from the carina or pleura. However, no study has evaluated the effects of the bronchoscope diameter. We evaluated whether the bronchoscope diameter affected the diagnostic yield of TBLB. METHODS: We reviewed records from 178 patients who underwent TBLB using bronchoscopes of two different diameters (5.7 mm, thick outer diameter, Olympus BF-200; 4.9 mm, thin, BF-260). The fluoroscopic guidance rates, yield of TBLB and flexible bronchoscopy (FB) were compared between the two groups. Additionally, we compared the results of the procedures with respect to diagnosis, distance from the pleura, and size of the lesion. RESULTS: The results of fluoroscopic guidance, TBLB, and FB yield using thin diameter bronchoscope were significantly better than those obtained with a thick diameter bronchoscope (p=0.021, p=0.036, and p=0.010, respectively). Particularly, when the distance from the pleura was ≤ 10 mm, success rates for fluoroscopic guidance and FB with thin bronchoscope were higher (p=0.013 and p=0.033, respectively), as compared to with thick bronchoscope. CONCLUSION: A thinner diameter bronchoscope increased the yield of bronchoscopy, and bronchial washing in conjunction with TBLB was useful in the diagnosis of peripheral pulmonary nodules.
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spelling pubmed-42867822015-01-11 The Effects of Bronchoscope Diameter on the Diagnostic Yield of Transbronchial Lung Biopsy of Peripheral Pulmonary Nodules Lee, Nakwon Kim, Sang-Ha Kwon, Woocheol Lee, Myoung Kyu Yong, Suk Joong Shin, Kye Chul Jung, Ye-Ryung Choi, Yeun Seoung Choi, Jiwon Choi, Ji Sun Lee, Won Yeon Tuberc Respir Dis (Seoul) Original Article BACKGROUND: Transbronchial lung biopsy (TBLB) is a valuable diagnostic tool for peripheral pulmonary lesions. The diagnostic yield of TBLB reportedly ranges from 41%-60%. Many studies demonstrated the various factors that influence the yield of TBLB, including size, location, and distance from the carina or pleura. However, no study has evaluated the effects of the bronchoscope diameter. We evaluated whether the bronchoscope diameter affected the diagnostic yield of TBLB. METHODS: We reviewed records from 178 patients who underwent TBLB using bronchoscopes of two different diameters (5.7 mm, thick outer diameter, Olympus BF-200; 4.9 mm, thin, BF-260). The fluoroscopic guidance rates, yield of TBLB and flexible bronchoscopy (FB) were compared between the two groups. Additionally, we compared the results of the procedures with respect to diagnosis, distance from the pleura, and size of the lesion. RESULTS: The results of fluoroscopic guidance, TBLB, and FB yield using thin diameter bronchoscope were significantly better than those obtained with a thick diameter bronchoscope (p=0.021, p=0.036, and p=0.010, respectively). Particularly, when the distance from the pleura was ≤ 10 mm, success rates for fluoroscopic guidance and FB with thin bronchoscope were higher (p=0.013 and p=0.033, respectively), as compared to with thick bronchoscope. CONCLUSION: A thinner diameter bronchoscope increased the yield of bronchoscopy, and bronchial washing in conjunction with TBLB was useful in the diagnosis of peripheral pulmonary nodules. The Korean Academy of Tuberculosis and Respiratory Diseases 2014-12 2014-12-31 /pmc/articles/PMC4286782/ /pubmed/25580141 http://dx.doi.org/10.4046/trd.2014.77.6.251 Text en Copyright©2014. The Korean Academy of Tuberculosis and Respiratory Diseases. All rights reserved. http://creativecommons.org/licenses/by-nc/3.0/ It is identical to the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/)
spellingShingle Original Article
Lee, Nakwon
Kim, Sang-Ha
Kwon, Woocheol
Lee, Myoung Kyu
Yong, Suk Joong
Shin, Kye Chul
Jung, Ye-Ryung
Choi, Yeun Seoung
Choi, Jiwon
Choi, Ji Sun
Lee, Won Yeon
The Effects of Bronchoscope Diameter on the Diagnostic Yield of Transbronchial Lung Biopsy of Peripheral Pulmonary Nodules
title The Effects of Bronchoscope Diameter on the Diagnostic Yield of Transbronchial Lung Biopsy of Peripheral Pulmonary Nodules
title_full The Effects of Bronchoscope Diameter on the Diagnostic Yield of Transbronchial Lung Biopsy of Peripheral Pulmonary Nodules
title_fullStr The Effects of Bronchoscope Diameter on the Diagnostic Yield of Transbronchial Lung Biopsy of Peripheral Pulmonary Nodules
title_full_unstemmed The Effects of Bronchoscope Diameter on the Diagnostic Yield of Transbronchial Lung Biopsy of Peripheral Pulmonary Nodules
title_short The Effects of Bronchoscope Diameter on the Diagnostic Yield of Transbronchial Lung Biopsy of Peripheral Pulmonary Nodules
title_sort effects of bronchoscope diameter on the diagnostic yield of transbronchial lung biopsy of peripheral pulmonary nodules
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286782/
https://www.ncbi.nlm.nih.gov/pubmed/25580141
http://dx.doi.org/10.4046/trd.2014.77.6.251
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