A Case of Organizing Pneumonia Associated with FOLFIRI Chemotherapy

The combination chemotherapy of irinotecan with 5-fluorouracil and leucovorin (FOLFIRI regimen) was recently proven to be beneficial in patients with advanced colorectal cancer. Pulmonary toxicity is very rare in adverse effects of irinotecan. No case of organizing pneumonia (also known as bronchiol...

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Autores principales: Lee, Yoon Jeong, Kim, Jun-Hyun, Kim, Sun Woong, Kang, Won Chan, Kim, Soo Jung, Kim, Ji Hye, Kim, Sun Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Tuberculosis and Respiratory Diseases 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286784/
https://www.ncbi.nlm.nih.gov/pubmed/25580143
http://dx.doi.org/10.4046/trd.2014.77.6.262
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author Lee, Yoon Jeong
Kim, Jun-Hyun
Kim, Sun Woong
Kang, Won Chan
Kim, Soo Jung
Kim, Ji Hye
Kim, Sun Jong
author_facet Lee, Yoon Jeong
Kim, Jun-Hyun
Kim, Sun Woong
Kang, Won Chan
Kim, Soo Jung
Kim, Ji Hye
Kim, Sun Jong
author_sort Lee, Yoon Jeong
collection PubMed
description The combination chemotherapy of irinotecan with 5-fluorouracil and leucovorin (FOLFIRI regimen) was recently proven to be beneficial in patients with advanced colorectal cancer. Pulmonary toxicity is very rare in adverse effects of irinotecan. No case of organizing pneumonia (also known as bronchiolitis obliterans organizing pneumonia) associated with FOLFIRI chemotherapy has been reported. We experienced a case of a 62-year-old man who presented persistent dry cough and progressive dyspnea after receiving chemotherapy with FOLFIRI regimen. After surgical lung biopsy, the patient was diagnosed with FOLFIRI chemotherapy-induced organizing pneumonia which was successfully treated with steroid therapy.
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spelling pubmed-42867842015-01-11 A Case of Organizing Pneumonia Associated with FOLFIRI Chemotherapy Lee, Yoon Jeong Kim, Jun-Hyun Kim, Sun Woong Kang, Won Chan Kim, Soo Jung Kim, Ji Hye Kim, Sun Jong Tuberc Respir Dis (Seoul) Case Report The combination chemotherapy of irinotecan with 5-fluorouracil and leucovorin (FOLFIRI regimen) was recently proven to be beneficial in patients with advanced colorectal cancer. Pulmonary toxicity is very rare in adverse effects of irinotecan. No case of organizing pneumonia (also known as bronchiolitis obliterans organizing pneumonia) associated with FOLFIRI chemotherapy has been reported. We experienced a case of a 62-year-old man who presented persistent dry cough and progressive dyspnea after receiving chemotherapy with FOLFIRI regimen. After surgical lung biopsy, the patient was diagnosed with FOLFIRI chemotherapy-induced organizing pneumonia which was successfully treated with steroid therapy. The Korean Academy of Tuberculosis and Respiratory Diseases 2014-12 2014-12-31 /pmc/articles/PMC4286784/ /pubmed/25580143 http://dx.doi.org/10.4046/trd.2014.77.6.262 Text en Copyright©2014. The Korean Academy of Tuberculosis and Respiratory Diseases. All rights reserved. http://creativecommons.org/licenses/by-nc/3.0/ It is identical to the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/)
spellingShingle Case Report
Lee, Yoon Jeong
Kim, Jun-Hyun
Kim, Sun Woong
Kang, Won Chan
Kim, Soo Jung
Kim, Ji Hye
Kim, Sun Jong
A Case of Organizing Pneumonia Associated with FOLFIRI Chemotherapy
title A Case of Organizing Pneumonia Associated with FOLFIRI Chemotherapy
title_full A Case of Organizing Pneumonia Associated with FOLFIRI Chemotherapy
title_fullStr A Case of Organizing Pneumonia Associated with FOLFIRI Chemotherapy
title_full_unstemmed A Case of Organizing Pneumonia Associated with FOLFIRI Chemotherapy
title_short A Case of Organizing Pneumonia Associated with FOLFIRI Chemotherapy
title_sort case of organizing pneumonia associated with folfiri chemotherapy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286784/
https://www.ncbi.nlm.nih.gov/pubmed/25580143
http://dx.doi.org/10.4046/trd.2014.77.6.262
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