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Role of excipients and polymeric advancements in preparation of floating drug delivery systems

Since decade or two, the development of floating drug delivery systems becomes a significant and novel tool as having low density than gastric content. There are various advanced polymers including chitosan, eudragit, etc., and excipients such as; pore forming agent, surfactants, etc. All of them ar...

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Detalles Bibliográficos
Autores principales: Kaushik, Avinash Y, Tiwari, Ajay K, Gaur, Ajay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286829/
https://www.ncbi.nlm.nih.gov/pubmed/25599027
http://dx.doi.org/10.4103/2230-973X.147219
Descripción
Sumario:Since decade or two, the development of floating drug delivery systems becomes a significant and novel tool as having low density than gastric content. There are various advanced polymers including chitosan, eudragit, etc., and excipients such as; pore forming agent, surfactants, etc. All of them are discussed briefly, and results are concluded from various reputed researches. We have discussed all natural and synthetic systems with their effect on the release and other parameters which are essential for the floating formulation development.