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Colon specific drug delivery of tramadol HCl for chronotherapeutics of arthritis
OBJECTIVE: The objective of present work is to develop and evaluate a matrix system for Chronotherapeutic delivery of centrally acting of opioid analgesic (tramadol HCl) to treat nocturnal symptoms of arthritis using almond gum as carrier. MATERIALS AND METHODS: Matrix tablets of tramadol HCl were p...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Medknow Publications & Media Pvt Ltd
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286834/ https://www.ncbi.nlm.nih.gov/pubmed/25599032 http://dx.doi.org/10.4103/2230-973X.147232 |