BMP4 and LGL1 are Down Regulated in an Ovine Model of Congenital Diaphragmatic Hernia

Background/Purpose: The molecular pathophysiology of lung hypoplasia in congenital diaphragmatic hernia (CDH) remains poorly understood. The Wnt signaling pathway and downstream targets, such as bone morphogenetic proteins (BMP) 4 and other factors such as late gestation lung protein 1 (LGL1), are e...

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Detalles Bibliográficos
Autores principales: Emmerton-Coughlin, Heather M. A., Martin, K. Kathryn, Chiu, Jacky S. S., Zhao, Lin, Scott, Leslie A., Regnault, Timothy R. H., Bütter, Andreana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Surgery
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286986/
https://www.ncbi.nlm.nih.gov/pubmed/25593968
http://dx.doi.org/10.3389/fsurg.2014.00044

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