DBC1/CCAR2 and CCAR1 Are Largely Disordered Proteins that Have Evolved from One Common Ancestor

Deleted in breast cancer 1 (DBC1, CCAR2, KIAA1967) is a large, predominantly nuclear, multidomain protein that modulates gene expression by inhibiting several epigenetic modifiers, including the deacetylases SIRT1 and HDAC3, and the methyltransferase SUV39H1. DBC1 shares many highly conserved protei...

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Detalles Bibliográficos
Autores principales: Brunquell, Jessica, Yuan, Jia, Erwin, Aqeela, Westerheide, Sandy D., Xue, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287135/
https://www.ncbi.nlm.nih.gov/pubmed/25610865
http://dx.doi.org/10.1155/2014/418458

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287135/
https://www.ncbi.nlm.nih.gov/pubmed/25610865
http://dx.doi.org/10.1155/2014/418458

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