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The biofilm matrix destabilizers, EDTA and DNaseI, enhance the susceptibility of nontypeable Hemophilus influenzae biofilms to treatment with ampicillin and ciprofloxacin

Nontypeable Hemophilus influenzae (NTHi) is a Gram-negative bacterial pathogen that causes chronic biofilm infections of the ears and airways. The biofilm matrix provides structural integrity to the biofilm and protects biofilm cells from antibiotic exposure by reducing penetration of antimicrobial...

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Detalles Bibliográficos
Autores principales:	Cavaliere, Rosalia, Ball, Jessica L, Turnbull, Lynne, Whitchurch, Cynthia B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287182/ https://www.ncbi.nlm.nih.gov/pubmed/25044339 http://dx.doi.org/10.1002/mbo3.187

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