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The Genetic and Mechanistic Basis for Variation in Gene Regulation
It is now well established that noncoding regulatory variants play a central role in the genetics of common diseases and in evolution. However, until recently, we have known little about the mechanisms by which most regulatory variants act. For instance, what types of functional elements in DNA, RNA...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287341/ https://www.ncbi.nlm.nih.gov/pubmed/25569255 http://dx.doi.org/10.1371/journal.pgen.1004857 |