Loss of presenilin 2 is associated with increased iPLA2 activity and lung tumor development

Presenilins are the enzymatic components of γ-secretase complex that cleaves amyloid precursor protein, Notch and β-catenin, which has critical roles in the development of Alzheimer's disease and cancer cell growth. Therefore, in the present study, we studied the effects and mechanisms of PS2 k...

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Detalles Bibliográficos
Autores principales: Yun, H-M, Park, M H, Kim, D H, Ahn, Y J, Park, K-R, Kim, T M, Yun, N Y, Jung, Y S, Hwang, D Y, Yoon, D Y, Han, S B, Hong, J T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287650/
https://www.ncbi.nlm.nih.gov/pubmed/24858037
http://dx.doi.org/10.1038/onc.2014.128

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