Distinct p21 requirements for regulating normal and self-reactive T cells through IFN-γ production

Self/non-self discrimination characterizes immunity and allows responses against pathogens but not self-antigens. Understanding the principles that govern this process is essential for designing autoimmunity treatments. p21 is thought to attenuate autoreactivity by limiting T cell expansion. Here, w...

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Detalles Bibliográficos
Autores principales: Daszkiewicz, Lidia, Vázquez-Mateo, Cristina, Rackov, Gorjana, Ballesteros-Tato, André, Weber, Kathrin, Madrigal-Avilés, Adrián, Di Pilato, Mauro, Fotedar, Arun, Fotedar, Rati, Flores, Juana M., Esteban, Mariano, Martínez-A, Carlos, Balomenos, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287747/
https://www.ncbi.nlm.nih.gov/pubmed/25573673
http://dx.doi.org/10.1038/srep07691

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