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Hydrocephalus in children less than 1 year of age in northern Mozambique

BACKGROUND: In developed countries, the incidence of neonatal hydrocephalus ranges from 3 to 5 cases per 1000 live births, but little is known about the frequency of hydrocephalus in Africa. In Mozambique, there is no primary information related to this disorder, but using the above data, the expect...

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Autores principales: Salvador, Sérgio F., Henriques, João Carlos, Munguambe, Missael, Vaz, Rui M. C., Barros, Henrique P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287916/
https://www.ncbi.nlm.nih.gov/pubmed/25593759
http://dx.doi.org/10.4103/2152-7806.146489
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author Salvador, Sérgio F.
Henriques, João Carlos
Munguambe, Missael
Vaz, Rui M. C.
Barros, Henrique P.
author_facet Salvador, Sérgio F.
Henriques, João Carlos
Munguambe, Missael
Vaz, Rui M. C.
Barros, Henrique P.
author_sort Salvador, Sérgio F.
collection PubMed
description BACKGROUND: In developed countries, the incidence of neonatal hydrocephalus ranges from 3 to 5 cases per 1000 live births, but little is known about the frequency of hydrocephalus in Africa. In Mozambique, there is no primary information related to this disorder, but using the above data, the expected incidence of neonatal hydrocephalus would range from 2900 to 4800 cases per year. METHODS: This study is based on 122 children younger than 1 year with neonatal hydrocephalus, followed up between January 2010 and December 2012, their origin and treatment, and aims to evaluate difficulties with diagnosis, treatment, and follow-up in northern Mozambique. RESULTS: Identified cases were mainly less than 6 months old (77%), with severe macrocephaly and the classic stigmata of this condition. A high rate of follow-up loss (44.3%) was detected, particularly among children from more distant locations. Our findings contrast with the expected 1000-1700 cases that would occur in the area during the study period, being considerably lower. CONCLUSIONS: Hydrocephalus is a serious problem in sub-Saharan Africa, whose effects can be minimized by a better organization of the health system in hydrocephalus prevention, referral, and follow-up. New management alternatives to provide treatment to more children with this disorder and reduction of the follow-up difficulties caused due to geographical reasons for the children undergoing treatment are essential.
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spelling pubmed-42879162015-01-15 Hydrocephalus in children less than 1 year of age in northern Mozambique Salvador, Sérgio F. Henriques, João Carlos Munguambe, Missael Vaz, Rui M. C. Barros, Henrique P. Surg Neurol Int Original Article BACKGROUND: In developed countries, the incidence of neonatal hydrocephalus ranges from 3 to 5 cases per 1000 live births, but little is known about the frequency of hydrocephalus in Africa. In Mozambique, there is no primary information related to this disorder, but using the above data, the expected incidence of neonatal hydrocephalus would range from 2900 to 4800 cases per year. METHODS: This study is based on 122 children younger than 1 year with neonatal hydrocephalus, followed up between January 2010 and December 2012, their origin and treatment, and aims to evaluate difficulties with diagnosis, treatment, and follow-up in northern Mozambique. RESULTS: Identified cases were mainly less than 6 months old (77%), with severe macrocephaly and the classic stigmata of this condition. A high rate of follow-up loss (44.3%) was detected, particularly among children from more distant locations. Our findings contrast with the expected 1000-1700 cases that would occur in the area during the study period, being considerably lower. CONCLUSIONS: Hydrocephalus is a serious problem in sub-Saharan Africa, whose effects can be minimized by a better organization of the health system in hydrocephalus prevention, referral, and follow-up. New management alternatives to provide treatment to more children with this disorder and reduction of the follow-up difficulties caused due to geographical reasons for the children undergoing treatment are essential. Medknow Publications & Media Pvt Ltd 2014-12-08 /pmc/articles/PMC4287916/ /pubmed/25593759 http://dx.doi.org/10.4103/2152-7806.146489 Text en Copyright: © 2014 Salvador SF. http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Original Article
Salvador, Sérgio F.
Henriques, João Carlos
Munguambe, Missael
Vaz, Rui M. C.
Barros, Henrique P.
Hydrocephalus in children less than 1 year of age in northern Mozambique
title Hydrocephalus in children less than 1 year of age in northern Mozambique
title_full Hydrocephalus in children less than 1 year of age in northern Mozambique
title_fullStr Hydrocephalus in children less than 1 year of age in northern Mozambique
title_full_unstemmed Hydrocephalus in children less than 1 year of age in northern Mozambique
title_short Hydrocephalus in children less than 1 year of age in northern Mozambique
title_sort hydrocephalus in children less than 1 year of age in northern mozambique
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287916/
https://www.ncbi.nlm.nih.gov/pubmed/25593759
http://dx.doi.org/10.4103/2152-7806.146489
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