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Toward Prospective Prediction of Pharmacokinetics in OATP1B1 Genetic Variant Populations

Physiologically based pharmacokinetic (PBPK) models are increasingly being used to provide human pharmacokinetic (PK) predictions for organic anion-transporting polypeptide (OATP) substrates based on in vitro assay data. As a natural extension in the application of these models, in this study, we in...

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Detalles Bibliográficos
Autores principales:	Li, R, Barton, H A, Maurer, T S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288003/ https://www.ncbi.nlm.nih.gov/pubmed/25494035 http://dx.doi.org/10.1038/psp.2014.50

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