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Depletion of REF/Aly alters gene expression and reduces RNA polymerase II occupancy
Pre-mRNA processing is mechanistically linked to transcription with RNA pol II serving as a platform to recruit RNA processing factors to nascent transcripts. The TREX complex member, REF/Aly, has been suggested to play roles in transcription and nuclear RNA stability in addition to its more broadly...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288173/ https://www.ncbi.nlm.nih.gov/pubmed/25477387 http://dx.doi.org/10.1093/nar/gku1278 |