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Synergic interplay of the La motif, RRM1 and the interdomain linker of LARP6 in the recognition of collagen mRNA expands the RNA binding repertoire of the La module

The La-related proteins (LARPs) form a diverse group of RNA-binding proteins characterized by the possession of a composite RNA binding unit, the La module. The La module comprises two domains, the La motif (LaM) and the RRM1, which together recognize and bind to a wide array of RNA substrates. Stru...

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Detalles Bibliográficos
Autores principales: Martino, Luigi, Pennell, Simon, Kelly, Geoff, Busi, Baptiste, Brown, Paul, Atkinson, R. Andrew, Salisbury, Nicholas J.H., Ooi, Zi-Hao, See, Kang-Wei, Smerdon, Stephen J., Alfano, Caterina, Bui, Tam T.T., Conte, Maria R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288179/
https://www.ncbi.nlm.nih.gov/pubmed/25488812
http://dx.doi.org/10.1093/nar/gku1287