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The histone demethylase enzyme KDM3A is a key estrogen receptor regulator in breast cancer
Endocrine therapy has successfully been used to treat estrogen receptor (ER)-positive breast cancer, but this invariably fails with cancers becoming refractory to treatment. Emerging evidence has suggested that fluctuations in ER co-regulatory protein expression may facilitate resistance to therapy...
Autores principales: | Wade, Mark A., Jones, Dominic, Wilson, Laura, Stockley, Jacqueline, Coffey, Kelly, Robson, Craig N., Gaughan, Luke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288188/ https://www.ncbi.nlm.nih.gov/pubmed/25488809 http://dx.doi.org/10.1093/nar/gku1298 |
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