Optimizing the data combination rule for seamless phase II/III clinical trials

We consider seamless phase II/III clinical trials that compare K treatments with a common control in phase II then test the most promising treatment against control in phase III. The final hypothesis test for the selected treatment can use data from both phases, subject to controlling the familywise...

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Detalles Bibliográficos
Autores principales: Hampson, Lisa V, Jennison, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288236/
https://www.ncbi.nlm.nih.gov/pubmed/25315892
http://dx.doi.org/10.1002/sim.6316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288236/
https://www.ncbi.nlm.nih.gov/pubmed/25315892
http://dx.doi.org/10.1002/sim.6316

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