Cargando…
Direct activation of STING in the tumor microenvironment with synthetic cyclic dinucleotide derivatives leads to potent and systemic tumor-specific immunity
Autores principales: | Corrales, Leticia, Glickman, Laura Hix, McWhirter, Sarah M, Kanne, David B, Sivick, Kelsey E, Lemmens, Edward, Leong, Justin J, Metchette, Ken, Dubensky, Thomas W, Gajewski, Thomas |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288314/ http://dx.doi.org/10.1186/2051-1426-2-S3-O10 |
Ejemplares similares
-
Modified STING-activating cyclic dinucleotide derivatives significantly enhance the anti-tumor activity of therapeutic vaccines
por: Leong, Meredith, et al.
Publicado: (2013) -
Cyclic dinucleotides (CDNs) reversed T cells tolerance in anti-tumor immunotherapy
por: Fu, Juan, et al.
Publicado: (2015) -
STING cyclic dinucleotide sensing originated in bacteria
por: Morehouse, Benjamin R., et al.
Publicado: (2020) -
Polymersome-mediated cytosolic delivery of cyclic dinucleotide STING agonist enhances tumor immunotherapy
por: Zheng, Huan, et al.
Publicado: (2022) -
STING inhibitors target the cyclic dinucleotide binding pocket
por: Hong, Ze, et al.
Publicado: (2021)