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RECQL1 and WRN DNA repair helicases: potential therapeutic targets and proliferative markers against cancers

RECQL1 and WRN helicases in the human RecQ helicase family participate in maintaining genome stability, DNA repair, replication, and recombination pathways in the cell cycle. They are expressed highly in rapidly proliferating cells and tumor cells, suggesting that they have important roles in the re...

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Detalles Bibliográficos
Autores principales: Futami, Kazunobu, Furuichi, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288340/
https://www.ncbi.nlm.nih.gov/pubmed/25620975
http://dx.doi.org/10.3389/fgene.2014.00441