Cargando…

Combination of a novel oncolytic immunotherapeutic agent, CAVATAK (coxsackievirus A21) and immune-checkpoint blockade significantly reduces tumor growth and improves survival in an immune competent mouse melanoma model

Detalles Bibliográficos
Autores principales: Shafren, Darren, Quah, Min, Wong, Yvonne, Andtbacka, Robert HI, Kaufman, Howard L, Au, Gough G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288429/
http://dx.doi.org/10.1186/2051-1426-2-S3-P125
_version_ 1782351971234086912
author Shafren, Darren
Quah, Min
Wong, Yvonne
Andtbacka, Robert HI
Kaufman, Howard L
Au, Gough G
author_facet Shafren, Darren
Quah, Min
Wong, Yvonne
Andtbacka, Robert HI
Kaufman, Howard L
Au, Gough G
author_sort Shafren, Darren
collection PubMed
description
format Online
Article
Text
id pubmed-4288429
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-42884292015-01-15 Combination of a novel oncolytic immunotherapeutic agent, CAVATAK (coxsackievirus A21) and immune-checkpoint blockade significantly reduces tumor growth and improves survival in an immune competent mouse melanoma model Shafren, Darren Quah, Min Wong, Yvonne Andtbacka, Robert HI Kaufman, Howard L Au, Gough G J Immunother Cancer Poster Presentation BioMed Central 2014-11-06 /pmc/articles/PMC4288429/ http://dx.doi.org/10.1186/2051-1426-2-S3-P125 Text en Copyright © 2014 Shafren et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Poster Presentation
Shafren, Darren
Quah, Min
Wong, Yvonne
Andtbacka, Robert HI
Kaufman, Howard L
Au, Gough G
Combination of a novel oncolytic immunotherapeutic agent, CAVATAK (coxsackievirus A21) and immune-checkpoint blockade significantly reduces tumor growth and improves survival in an immune competent mouse melanoma model
title Combination of a novel oncolytic immunotherapeutic agent, CAVATAK (coxsackievirus A21) and immune-checkpoint blockade significantly reduces tumor growth and improves survival in an immune competent mouse melanoma model
title_full Combination of a novel oncolytic immunotherapeutic agent, CAVATAK (coxsackievirus A21) and immune-checkpoint blockade significantly reduces tumor growth and improves survival in an immune competent mouse melanoma model
title_fullStr Combination of a novel oncolytic immunotherapeutic agent, CAVATAK (coxsackievirus A21) and immune-checkpoint blockade significantly reduces tumor growth and improves survival in an immune competent mouse melanoma model
title_full_unstemmed Combination of a novel oncolytic immunotherapeutic agent, CAVATAK (coxsackievirus A21) and immune-checkpoint blockade significantly reduces tumor growth and improves survival in an immune competent mouse melanoma model
title_short Combination of a novel oncolytic immunotherapeutic agent, CAVATAK (coxsackievirus A21) and immune-checkpoint blockade significantly reduces tumor growth and improves survival in an immune competent mouse melanoma model
title_sort combination of a novel oncolytic immunotherapeutic agent, cavatak (coxsackievirus a21) and immune-checkpoint blockade significantly reduces tumor growth and improves survival in an immune competent mouse melanoma model
topic Poster Presentation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288429/
http://dx.doi.org/10.1186/2051-1426-2-S3-P125
work_keys_str_mv AT shafrendarren combinationofanoveloncolyticimmunotherapeuticagentcavatakcoxsackievirusa21andimmunecheckpointblockadesignificantlyreducestumorgrowthandimprovessurvivalinanimmunecompetentmousemelanomamodel
AT quahmin combinationofanoveloncolyticimmunotherapeuticagentcavatakcoxsackievirusa21andimmunecheckpointblockadesignificantlyreducestumorgrowthandimprovessurvivalinanimmunecompetentmousemelanomamodel
AT wongyvonne combinationofanoveloncolyticimmunotherapeuticagentcavatakcoxsackievirusa21andimmunecheckpointblockadesignificantlyreducestumorgrowthandimprovessurvivalinanimmunecompetentmousemelanomamodel
AT andtbackaroberthi combinationofanoveloncolyticimmunotherapeuticagentcavatakcoxsackievirusa21andimmunecheckpointblockadesignificantlyreducestumorgrowthandimprovessurvivalinanimmunecompetentmousemelanomamodel
AT kaufmanhowardl combinationofanoveloncolyticimmunotherapeuticagentcavatakcoxsackievirusa21andimmunecheckpointblockadesignificantlyreducestumorgrowthandimprovessurvivalinanimmunecompetentmousemelanomamodel
AT augoughg combinationofanoveloncolyticimmunotherapeuticagentcavatakcoxsackievirusa21andimmunecheckpointblockadesignificantlyreducestumorgrowthandimprovessurvivalinanimmunecompetentmousemelanomamodel