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Intensive chemotherapy as salvage treatment for solid tumors: focus on germ cell cancer

Germ cell tumors present contrasting biological and molecular features compared to many solid tumors, which may partially explain their unusual sensitivity to chemotherapy. Reduced DNA repair capacity and enhanced induction of apoptosis appear to be key factors in the sensitivity of germ cell tumors...

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Detalles Bibliográficos
Autores principales:	Selle, F., Gligorov, J., Richard, S., Khalil, A., Alexandre, I., Avenin, D., Provent, S., Soares, D.G., Lotz, J.P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Associação Brasileira de Divulgação Científica 2014
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288488/ https://www.ncbi.nlm.nih.gov/pubmed/25493378 http://dx.doi.org/10.1590/1414-431X20144214

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