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Systems Level Analysis of Systemic Sclerosis Shows a Network of Immune and Profibrotic Pathways Connected with Genetic Polymorphisms
Systemic sclerosis (SSc) is a rare systemic autoimmune disease characterized by skin and organ fibrosis. The pathogenesis of SSc and its progression are poorly understood. The SSc intrinsic gene expression subsets (inflammatory, fibroproliferative, normal-like, and limited) are observed in multiple...
Autores principales: | Mahoney, J. Matthew, Taroni, Jaclyn, Martyanov, Viktor, Wood, Tammara A., Greene, Casey S., Pioli, Patricia A., Hinchcliff, Monique E., Whitfield, Michael L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288710/ https://www.ncbi.nlm.nih.gov/pubmed/25569146 http://dx.doi.org/10.1371/journal.pcbi.1004005 |
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