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Wnt signaling is involved in 6-benzylthioinosine-induced AML cell differentiation

BACKGROUND: We previously demonstrated that 6-benzylthioinosine (6-BT) could induce the differentiation of a subset of acute myeloid leukemia (AML) cell lines and primary AML cells regardless of their cytogenetics. In this study we investigated whether Wnt signaling pathways played roles in 6-BT-ind...

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Detalles Bibliográficos
Autores principales: Zang, Shaolei, Liu, Na, Wang, Hongchun, Wald, David N, Shao, Na, Zhang, Jingru, Ma, Daoxin, Ji, Chunyan, Tse, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289047/
https://www.ncbi.nlm.nih.gov/pubmed/25428027
http://dx.doi.org/10.1186/1471-2407-14-886