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Cost-effectiveness of larviciding for urban malaria control in Tanzania

BACKGROUND: Larviciding for malaria control can contribute to an Integrated Vector Management (IVM) approach. This intervention is currently supported in settings where breeding habitats are ‘few, fixed, and findable’, such as urban areas of sub-Saharan Africa, but the knowledge base regarding the c...

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Autores principales: Maheu-Giroux, Mathieu, Castro, Marcia C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289051/
https://www.ncbi.nlm.nih.gov/pubmed/25476586
http://dx.doi.org/10.1186/1475-2875-13-477
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author Maheu-Giroux, Mathieu
Castro, Marcia C
author_facet Maheu-Giroux, Mathieu
Castro, Marcia C
author_sort Maheu-Giroux, Mathieu
collection PubMed
description BACKGROUND: Larviciding for malaria control can contribute to an Integrated Vector Management (IVM) approach. This intervention is currently supported in settings where breeding habitats are ‘few, fixed, and findable’, such as urban areas of sub-Saharan Africa, but the knowledge base regarding the cost-effectiveness of larviciding is non-existent. METHODS: Programme costs and effectiveness data were collected from the Dar es Salaam Urban Malaria Control Programme in Tanzania. Cost-effectiveness ratios (CER) were estimated from the provider and societal perspectives for standard indicators using different malaria transmission scenarios. RESULTS: CER for microbial larviciding were highly dependent on the assumed baseline malaria incidence rates. Using the societal perspective, net CER were estimated (in 2012 US dollars) at $43 (95% uncertainty intervals [UI]: $15-181) per disability-adjusted life year averted (DALY) when malaria incidence was 902 infections per 1,000 individuals, increasing to $545 (95% UI: $337-1,558) per DALY at an incidence of 122 per 1,000. Larviciding was shown to be cost-effective in Tanzania for incidences as low as 40 infections per 1,000 people per year. CONCLUSION: This is believed to be the first study to estimate the cost-effectiveness of larviciding for urban malaria control in sub-Saharan Africa. The results support the use of larviciding as a cost-effective intervention in urban areas and managers of national malaria control programme should consider this intervention as part of an IVM approach. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/1475-2875-13-477) contains supplementary material, which is available to authorized users.
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spelling pubmed-42890512015-01-11 Cost-effectiveness of larviciding for urban malaria control in Tanzania Maheu-Giroux, Mathieu Castro, Marcia C Malar J Research BACKGROUND: Larviciding for malaria control can contribute to an Integrated Vector Management (IVM) approach. This intervention is currently supported in settings where breeding habitats are ‘few, fixed, and findable’, such as urban areas of sub-Saharan Africa, but the knowledge base regarding the cost-effectiveness of larviciding is non-existent. METHODS: Programme costs and effectiveness data were collected from the Dar es Salaam Urban Malaria Control Programme in Tanzania. Cost-effectiveness ratios (CER) were estimated from the provider and societal perspectives for standard indicators using different malaria transmission scenarios. RESULTS: CER for microbial larviciding were highly dependent on the assumed baseline malaria incidence rates. Using the societal perspective, net CER were estimated (in 2012 US dollars) at $43 (95% uncertainty intervals [UI]: $15-181) per disability-adjusted life year averted (DALY) when malaria incidence was 902 infections per 1,000 individuals, increasing to $545 (95% UI: $337-1,558) per DALY at an incidence of 122 per 1,000. Larviciding was shown to be cost-effective in Tanzania for incidences as low as 40 infections per 1,000 people per year. CONCLUSION: This is believed to be the first study to estimate the cost-effectiveness of larviciding for urban malaria control in sub-Saharan Africa. The results support the use of larviciding as a cost-effective intervention in urban areas and managers of national malaria control programme should consider this intervention as part of an IVM approach. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/1475-2875-13-477) contains supplementary material, which is available to authorized users. BioMed Central 2014-12-04 /pmc/articles/PMC4289051/ /pubmed/25476586 http://dx.doi.org/10.1186/1475-2875-13-477 Text en © Maheu-Giroux and Castro; licensee BioMed Central Ltd. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Maheu-Giroux, Mathieu
Castro, Marcia C
Cost-effectiveness of larviciding for urban malaria control in Tanzania
title Cost-effectiveness of larviciding for urban malaria control in Tanzania
title_full Cost-effectiveness of larviciding for urban malaria control in Tanzania
title_fullStr Cost-effectiveness of larviciding for urban malaria control in Tanzania
title_full_unstemmed Cost-effectiveness of larviciding for urban malaria control in Tanzania
title_short Cost-effectiveness of larviciding for urban malaria control in Tanzania
title_sort cost-effectiveness of larviciding for urban malaria control in tanzania
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289051/
https://www.ncbi.nlm.nih.gov/pubmed/25476586
http://dx.doi.org/10.1186/1475-2875-13-477
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