Primitive neuroectodermal tumor (PNET) of the lung in an adult woman

Primary primitive neuroectodermal tumors (PNETs) are extremely rare in the lung and especially in adult women. We describe a case of PNET of the lung with aggressive behavior in 31-year-old woman. Diagnosis was based on histopathological and immunohistochemical studies, and confirmed by molecular ge...

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Detalles Bibliográficos
Autores principales: Gachechiladze, Mariam, Škarda, Josef, Ibrahim, Maha, Tichý, Tomáš, Flodr, Patrik, Latálová, Pavla, Ehrmann, Jiří, Trojanec, Radek, Kolář, Zdenek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289161/
https://www.ncbi.nlm.nih.gov/pubmed/25475214
http://dx.doi.org/10.1186/1477-7819-12-374
Descripción
Sumario:Primary primitive neuroectodermal tumors (PNETs) are extremely rare in the lung and especially in adult women. We describe a case of PNET of the lung with aggressive behavior in 31-year-old woman. Diagnosis was based on histopathological and immunohistochemical studies, and confirmed by molecular genetic analysis of chromosome rearrangements in the EWSR1 gene region. Clinical follow-up, post-mortem findings, and differential diagnosis are also discussed. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/1477-7819-12-374) contains supplementary material, which is available to authorized users.

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