Primitive neuroectodermal tumor (PNET) of the lung in an adult woman

Primary primitive neuroectodermal tumors (PNETs) are extremely rare in the lung and especially in adult women. We describe a case of PNET of the lung with aggressive behavior in 31-year-old woman. Diagnosis was based on histopathological and immunohistochemical studies, and confirmed by molecular ge...

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Autores principales: Gachechiladze, Mariam, Škarda, Josef, Ibrahim, Maha, Tichý, Tomáš, Flodr, Patrik, Latálová, Pavla, Ehrmann, Jiří, Trojanec, Radek, Kolář, Zdenek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289161/
https://www.ncbi.nlm.nih.gov/pubmed/25475214
http://dx.doi.org/10.1186/1477-7819-12-374
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author Gachechiladze, Mariam
Škarda, Josef
Ibrahim, Maha
Tichý, Tomáš
Flodr, Patrik
Latálová, Pavla
Ehrmann, Jiří
Trojanec, Radek
Kolář, Zdenek
author_facet Gachechiladze, Mariam
Škarda, Josef
Ibrahim, Maha
Tichý, Tomáš
Flodr, Patrik
Latálová, Pavla
Ehrmann, Jiří
Trojanec, Radek
Kolář, Zdenek
author_sort Gachechiladze, Mariam
collection PubMed
description Primary primitive neuroectodermal tumors (PNETs) are extremely rare in the lung and especially in adult women. We describe a case of PNET of the lung with aggressive behavior in 31-year-old woman. Diagnosis was based on histopathological and immunohistochemical studies, and confirmed by molecular genetic analysis of chromosome rearrangements in the EWSR1 gene region. Clinical follow-up, post-mortem findings, and differential diagnosis are also discussed. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/1477-7819-12-374) contains supplementary material, which is available to authorized users.
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spelling pubmed-42891612015-01-11 Primitive neuroectodermal tumor (PNET) of the lung in an adult woman Gachechiladze, Mariam Škarda, Josef Ibrahim, Maha Tichý, Tomáš Flodr, Patrik Latálová, Pavla Ehrmann, Jiří Trojanec, Radek Kolář, Zdenek World J Surg Oncol Case Report Primary primitive neuroectodermal tumors (PNETs) are extremely rare in the lung and especially in adult women. We describe a case of PNET of the lung with aggressive behavior in 31-year-old woman. Diagnosis was based on histopathological and immunohistochemical studies, and confirmed by molecular genetic analysis of chromosome rearrangements in the EWSR1 gene region. Clinical follow-up, post-mortem findings, and differential diagnosis are also discussed. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/1477-7819-12-374) contains supplementary material, which is available to authorized users. BioMed Central 2014-12-05 /pmc/articles/PMC4289161/ /pubmed/25475214 http://dx.doi.org/10.1186/1477-7819-12-374 Text en © Gachechiladze et al.; licensee BioMed Central Ltd. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Gachechiladze, Mariam
Škarda, Josef
Ibrahim, Maha
Tichý, Tomáš
Flodr, Patrik
Latálová, Pavla
Ehrmann, Jiří
Trojanec, Radek
Kolář, Zdenek
Primitive neuroectodermal tumor (PNET) of the lung in an adult woman
title Primitive neuroectodermal tumor (PNET) of the lung in an adult woman
title_full Primitive neuroectodermal tumor (PNET) of the lung in an adult woman
title_fullStr Primitive neuroectodermal tumor (PNET) of the lung in an adult woman
title_full_unstemmed Primitive neuroectodermal tumor (PNET) of the lung in an adult woman
title_short Primitive neuroectodermal tumor (PNET) of the lung in an adult woman
title_sort primitive neuroectodermal tumor (pnet) of the lung in an adult woman
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289161/
https://www.ncbi.nlm.nih.gov/pubmed/25475214
http://dx.doi.org/10.1186/1477-7819-12-374
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