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Dynamics of double strand breaks and chromosomal translocations
Chromosomal translocations are a major cause of cancer. At the same time, the mechanisms that lead to specific chromosomal translocations that associate different gene regions remain largely unknown. Translocations are induced by double strand breaks (DSBs) in DNA. Here we review recent data on the...
Autores principales: | Iarovaia, Olga V, Rubtsov, Mikhail, Ioudinkova, Elena, Tsfasman, Tatiana, Razin, Sergey V, Vassetzky, Yegor S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289179/ https://www.ncbi.nlm.nih.gov/pubmed/25404525 http://dx.doi.org/10.1186/1476-4598-13-249 |
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