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Dose-dependent effects of lesogaberan on reflux measures in patients with refractory gastroesophageal reflux disease: a randomized, placebo-controlled study
BACKGROUND: The γ-aminobutyric acid type B-receptor agonist lesogaberan (AZD3355) has been developed for use in patients with gastroesophageal reflux disease (GERD) symptoms despite proton pump inhibitor (PPI) therapy (partial responders). This study aimed to explore the dose–response effect of leso...
Autores principales: | Miner, Philip B, Silberg, Debra G, Ruth, Magnus, Miller, Frank, Pandolfino, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289246/ https://www.ncbi.nlm.nih.gov/pubmed/25407279 http://dx.doi.org/10.1186/1471-230X-14-188 |
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