CryptoDex: A randomised, double-blind, placebo-controlled phase III trial of adjunctive dexamethasone in HIV-infected adults with cryptococcal meningitis: study protocol for a randomised control trial

BACKGROUND: Cryptococcal meningitis (CM) is a severe AIDS-defining illness with 90-day case mortality as high as 70% in sub-Saharan Africa, despite treatment. It is the leading cause of death in HIV patients in Asia and Africa. No major advance has been made in the treatment of CM since the 1970s. T...

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Detalles Bibliográficos
Autores principales: Day, Jeremy, Imran, Darma, Ganiem, Ahmed Rizal, Tjahjani, Natriana, Wahyuningsih, Retno, Adawiyah, Robiatul, Dance, David, Mayxay, Mayfong, Newton, Paul, Phetsouvanh, Rattanaphone, Rattanavong, Sayaphet, Chan, Adrienne K, Heyderman, Robert, van Oosterhout, Joep J, Chierakul, Wirongrong, Day, Nick, Kamali, Anatoli, Kibengo, Freddie, Ruzagira, Eugene, Gray, Alastair, Lalloo, David G, Beardsley, Justin, Binh, Tran Quang, Chau, Tran Thi Hong, Chau, Nguyen Van Vinh, Cuc, Ngo Thi Kim, Farrar, Jeremy, Hien, Tran Tinh, Van Kinh, Nguyen, Merson, Laura, Phuong, Lan, Tho, Loc Truong, Thuy, Pham Thanh, Thwaites, Guy, Wertheim, Heiman, Wolbers, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289250/
https://www.ncbi.nlm.nih.gov/pubmed/25391338
http://dx.doi.org/10.1186/1745-6215-15-441

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