Cargando…
Innate lymphoid cells and the skin
Innate lymphoid cells are an emerging family of effector cells that contribute to lymphoid organogenesis, metabolism, tissue remodelling and protection against infections. They maintain homeostatic immunity at barrier surfaces such as lung, skin and gut (Nature 464:1367–1371, 2010, Nat Rev Immunol 1...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289267/ https://www.ncbi.nlm.nih.gov/pubmed/25427661 http://dx.doi.org/10.1186/1471-5945-14-18 |
_version_ | 1782352079912697856 |
---|---|
author | Salimi, Maryam Ogg, Graham |
author_facet | Salimi, Maryam Ogg, Graham |
author_sort | Salimi, Maryam |
collection | PubMed |
description | Innate lymphoid cells are an emerging family of effector cells that contribute to lymphoid organogenesis, metabolism, tissue remodelling and protection against infections. They maintain homeostatic immunity at barrier surfaces such as lung, skin and gut (Nature 464:1367–1371, 2010, Nat Rev Immunol 13: 145–149, 2013). Several human and mouse studies suggest a role for innate lymphoid cells in inflammatory skin conditions including atopic eczema and psoriasis. Here we review the innate lymphoid cell family and discuss their function in the skin and during inflammation. |
format | Online Article Text |
id | pubmed-4289267 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-42892672015-01-11 Innate lymphoid cells and the skin Salimi, Maryam Ogg, Graham BMC Dermatol Review Innate lymphoid cells are an emerging family of effector cells that contribute to lymphoid organogenesis, metabolism, tissue remodelling and protection against infections. They maintain homeostatic immunity at barrier surfaces such as lung, skin and gut (Nature 464:1367–1371, 2010, Nat Rev Immunol 13: 145–149, 2013). Several human and mouse studies suggest a role for innate lymphoid cells in inflammatory skin conditions including atopic eczema and psoriasis. Here we review the innate lymphoid cell family and discuss their function in the skin and during inflammation. BioMed Central 2014-11-26 /pmc/articles/PMC4289267/ /pubmed/25427661 http://dx.doi.org/10.1186/1471-5945-14-18 Text en © Salimi and Ogg; licensee BioMed Central Ltd. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Review Salimi, Maryam Ogg, Graham Innate lymphoid cells and the skin |
title | Innate lymphoid cells and the skin |
title_full | Innate lymphoid cells and the skin |
title_fullStr | Innate lymphoid cells and the skin |
title_full_unstemmed | Innate lymphoid cells and the skin |
title_short | Innate lymphoid cells and the skin |
title_sort | innate lymphoid cells and the skin |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289267/ https://www.ncbi.nlm.nih.gov/pubmed/25427661 http://dx.doi.org/10.1186/1471-5945-14-18 |
work_keys_str_mv | AT salimimaryam innatelymphoidcellsandtheskin AT ogggraham innatelymphoidcellsandtheskin |