DNA copy number evolution in Drosophila cell lines

BACKGROUND: Structural rearrangements of the genome resulting in genic imbalance due to copy number change are often deleterious at the organismal level, but are common in immortalized cell lines and tumors, where they may be an advantage to cells. In order to explore the biological consequences of...

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Detalles Bibliográficos
Autores principales: Lee, Hangnoh, McManus, C Joel, Cho, Dong-Yeon, Eaton, Matthew, Renda, Fioranna, Somma, Maria Patrizia, Cherbas, Lucy, May, Gemma, Powell, Sara, Zhang, Dayu, Zhan, Lijun, Resch, Alissa, Andrews, Justen, Celniker, Susan E, Cherbas, Peter, Przytycka, Teresa M, Gatti, Maurizio, Oliver, Brian, Graveley, Brenton, MacAlpine, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289277/
https://www.ncbi.nlm.nih.gov/pubmed/25262759
http://dx.doi.org/10.1186/gb-2014-15-8-r70

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