P7170, a novel inhibitor of mTORC1/mTORC2 and Activin receptor-like Kinase 1 (ALK1) inhibits the growth of non small cell lung cancer

BACKGROUND: Lung cancer is the major cause of cancer-related deaths and many cases of Non Small Cell Lung Cancer (NSCLC), a common type of lung cancer, have frequent genetic/oncogenic activation of EGFR, KRAS, PIK3CA, BRAF, and others that drive tumor growth. Some patients though initially respond,...

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Detalles Bibliográficos
Autores principales: Venkatesha, Venkatasubbaiah A, Joshi, Asavari, Venkataraman, Magesh, Sonawane, Vinay, Bhatia, Dimple, Tannu, Prashant, Bose, Julie, Choudhari, Sarika, Srivastava, Ankita, Pandey, Prashant Kumar, Lad, Vaibhavi J, Sangana, Ramachandra, Ahmed, Tausif, Damre, Anagha, Deore, Vijaykumar, Sahu, Bichismita, Kumar, Sanjay, Sharma, Somesh, Agarwal, Veena R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289333/
https://www.ncbi.nlm.nih.gov/pubmed/25466244
http://dx.doi.org/10.1186/1476-4598-13-259

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