Cargando…

Predicting response to vascular endothelial growth factor inhibitor and chemotherapy in metastatic colorectal cancer

BACKGROUND: Bevacizumab improves progression free survival (PFS) and overall survival (OS) in metastatic colorectal cancer patients however currently there are no biomarkers that predict response to this treatment. The aim of this study was to assess if differential protein expression can differenti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Martin, Petra, Noonan, Sinead, Mullen, Michael P, Scaife, Caitriona, Tosetto, Miriam, Nolan, Blathnaid, Wynne, Kieran, Hyland, John, Sheahan, Kieran, Elia, Giuliano, O’Donoghue, Diarmuid, Fennelly, David, O’Sullivan, Jacintha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289341/ https://www.ncbi.nlm.nih.gov/pubmed/25428203 http://dx.doi.org/10.1186/1471-2407-14-887

Ejemplares similares

Tumour vasculature immaturity, oxidative damage and systemic inflammation stratify survival of colorectal cancer patients on bevacizumab treatment
por: Noonan, Sinead A., et al.
Publicado: (2018)

Preclinical validation of the small molecule drug quininib as a novel therapeutic for colorectal cancer
por: Murphy, Adrian G., et al.
Publicado: (2016)

Tumour Tissue Microenvironment Can Inhibit Dendritic Cell Maturation in Colorectal Cancer
por: Michielsen, Adriana J., et al.
Publicado: (2011)

Nuclear oxidative damage correlates with poor survival in colorectal cancer
por: Sheridan, J, et al.
Publicado: (2009)

Characterising the prognostic potential of HLA-DR during colorectal cancer development
por: Dunne, Margaret R., et al.
Publicado: (2020)

The Associations of Selenoprotein Genetic Variants with the Risks of Colorectal Adenoma and Colorectal Cancer: Case–Control Studies in Irish and Czech Populations
por: Mukhtar, Maryam, et al.
Publicado: (2022)

Tumour microenvironment of both early- and late-stage colorectal cancer is equally immunosuppressive
por: O'Toole, A, et al.
Publicado: (2014)

Enrichment of Inflammatory IL-17 and TNF-α Secreting CD4(+) T Cells within Colorectal Tumors despite the Presence of Elevated CD39(+) T Regulatory Cells and Increased Expression of the Immune Checkpoint Molecule, PD-1
por: Dunne, Margaret R., et al.
Publicado: (2016)

Decreased Mitochondrial DNA Mutagenesis in Human Colorectal Cancer
por: Ericson, Nolan G., et al.
Publicado: (2012)

Metastatic Melanoma presenting 24 years after surgical resection: a case report and review of the literature
por: Slattery, Eoin, et al.
Publicado: (2009)

Heterogeneity of tumor-induced gene expression changes in the human metabolic network
por: Hu, Jie, et al.
Publicado: (2013)

Anorectal stenosis after treatment with tumor necrosis factor α antibodies: a case series
por: Slattery, Eoin, et al.
Publicado: (2010)

Depth-Dependent Differences in Community Structure of the Human Colonic Microbiota in Health
por: Lavelle, Aonghus, et al.
Publicado: (2013)

Omega-3 fatty acid deficiency disrupts endocytosis, neuritogenesis, and mitochondrial protein pathways in the mouse hippocampus
por: English, Jane A., et al.
Publicado: (2013)

Dataset of mouse hippocampus profiled by LC–MS/MS for label-free quantitation
por: English, Jane A., et al.
Publicado: (2016)

A qualitative exploration of obesity bias and stigma in Irish healthcare; the patients’ voice
por: O’Donoghue, Grainne, et al.
Publicado: (2021)

The effect of combined action observation therapy and eccentric exercises in the treatment of mid-portion Achilles tendinopathy: study protocol for a feasibility pilot randomised controlled trial
por: Ryan, Deirdre, et al.
Publicado: (2022)

“I’ve got a spring in my step” participants experience of action observation therapy and eccentric exercises, a telehealth study for mid-portion Achilles Tendinopathy: a qualitative study
por: Ryan, Deirdre, et al.
Publicado: (2023)

Butyrate limits human natural killer cell effector function
por: Zaiatz-Bittencourt, Vanessa, et al.
Publicado: (2023)

The effect of combined Action Observation Therapy with eccentric exercises in the treatment of mid-portion Achilles-tendinopathy: a feasibility pilot randomised controlled trial
por: Ryan, Deirdre, et al.
Publicado: (2022)

Cognitive functional therapy compared with a group-based exercise and education intervention for chronic low back pain: a multicentre randomised controlled trial (RCT)
por: O'Keeffe, Mary, et al.
Publicado: (2020)

What exercise prescription is optimal to improve body composition and cardiorespiratory fitness in adults living with obesity? A network meta‐analysis
por: O'Donoghue, Grainne, et al.
Publicado: (2020)

Screening for mismatch repair deficiency in colorectal cancer: data from three academic medical centers
por: O'Kane, Grainne M., et al.
Publicado: (2017)

The effect of warm-up, static stretching and dynamic stretching on hamstring flexibility in previously injured subjects
por: O'Sullivan, Kieran, et al.
Publicado: (2009)

The Beliefs of Third-Level Healthcare Students towards Low-Back Pain
por: Kennedy, Norelee, et al.
Publicado: (2014)

Personalised mapping of tumour development in synchronous colorectal cancer patients
por: Thomas, Valentina, et al.
Publicado: (2020)

A Validation Study of a Polymer Optical Fiber Sensor for Monitoring Lumbar Spine Movement
por: Kam, Wern, et al.
Publicado: (2019)

Exposure and attitudes to adolescent health amongst Paediatric trainees in Northern Ireland: a mixed-methods study
por: Mullen, Stephen, et al.
Publicado: (2020)

Electromyographic analysis of the three subdivisions of gluteus medius during weight-bearing exercises
por: O'Sullivan, Kieran, et al.
Publicado: (2010)

Spatial variation of the colonic microbiota in patients with ulcerative colitis and control volunteers
por: Lavelle, A, et al.
Publicado: (2015)

Differential expression and upregulation of interleukin-1alpha, interleukin-1beta and interleukin-6 by freshly isolated human small intestinal epithelial cells.
por: Madrigal-Estebas, Laura, et al.
Publicado: (2002)

Prognostic, Diagnostic and Predictive Biomarkers in the Barrett’s Oesophagus-Adenocarcinoma Disease Sequence
por: O’Dowd, Darragh, et al.
Publicado: (2022)

Comparison of time-matched aerobic, resistance or combined exercise training in women living with obesity: a protocol for a pilot randomised controlled trial—the EXOFFIT (Exercise for Obesity in Females to increase Fitness) study
por: Davis, Mary E., et al.
Publicado: (2022)

Interventions to improve wellbeing among obstetricians and midwives at Cork University Maternity Hospital
por: O’Riordan, Sinead, et al.
Publicado: (2019)

Lifestyle Interventions to Improve Glycemic Control in Adults with Type 2 Diabetes Living in Low-and-Middle Income Countries: A Systematic Review and Meta-Analysis of Randomized Controlled Trials (RCTs)
por: O’Donoghue, Grainne, et al.
Publicado: (2021)

A qualitative review of challenges in recruitment and retention in obstetrics and gynecology in Ireland: The consultants’ solution based perspective
por: McCarthy, Claire M., et al.
Publicado: (2022)

The relationship between previous hamstring injury and the concentric isokinetic knee muscle strength of irish gaelic footballers
por: O'Sullivan, Kieran, et al.
Publicado: (2008)

Economic Assessment of Waterborne Outbreak of Cryptosporidiosis
por: Chyzheuskaya, Aksana, et al.
Publicado: (2017)

Exploring the Glycosylation of Serum CA125
por: Saldova, Radka, et al.
Publicado: (2013)

The effect of low-dye taping on rearfoot motion and plantar pressure during the stance phase of gait
por: O'Sullivan, Kieran, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_uka4prgkn96qdm94dpomrr13g7