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Biopolymer implants enhance the efficacy of adoptive T cell therapy

Although adoptive T cell therapy holds promise for the treatment of many cancers, its clinical utility has been limited by problems in delivering targeted lymphocytes to tumor sites, and their inefficient expansion in the immunosuppressive tumor microenvironment. Here we describe a bioactive polymer...

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Detalles Bibliográficos
Autores principales: Stephan, Sirkka B., Taber, Alexandria M., Jileaeva, Ilona, Pegues, Ericka P., Sentman, Charles L., Stephan, Matthias T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289408/
https://www.ncbi.nlm.nih.gov/pubmed/25503382
http://dx.doi.org/10.1038/nbt.3104

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