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A Monte Carlo Study for Photoneutron Dose Estimations around the High-Energy Linacs

Background: High-energy linear accelerator (linac) is a valuable tool and the most commonly used device for external beam radiation treatments in cancer patients. In the linac head, high-energy photons with energies above the threshold of (γ,n) interaction produce photoneutrons. These photoneutrons...

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Autores principales: Mohammadi, N, Miri-Hakimabad, S H, Rafat-Motavalli, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shiraz University of Medical Sciences 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289520/
https://www.ncbi.nlm.nih.gov/pubmed/25599059
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author Mohammadi, N
Miri-Hakimabad, S H
Rafat-Motavalli, L
author_facet Mohammadi, N
Miri-Hakimabad, S H
Rafat-Motavalli, L
author_sort Mohammadi, N
collection PubMed
description Background: High-energy linear accelerator (linac) is a valuable tool and the most commonly used device for external beam radiation treatments in cancer patients. In the linac head, high-energy photons with energies above the threshold of (γ,n) interaction produce photoneutrons. These photoneutrons deliver the extra dose to the patients undergoing radiation treatment and increase the risk of secondary cancer. Objective: In this study, a simplified model of the linac head was simulated and photoneutron dose equivalent was calculated at the isocenter and maze in the sphere detector. In addition, the absorbed and equivalent dose of photoneutron were estimated in the some organs of the phantom. Methods: The simulations were made using the Monte Carlo code. The ICRP reference adult male voxel phantom was used as the human body model for dosimetry calculations. Results: The results of dose calculations at the isocenter and maze showed that photoneutron dose decreases as the function of distance from the isocenter and increases with increasing the distance from the entrance maze. Conclusion: It is concluded that the simplified model of linac head is a useful and reliable method in dosimetry calculations. Calculations illustrated that the photoneutron dose is not negligible and duo to its harmful biological effects on body, it should be considered in the treatment plans.
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spelling pubmed-42895202015-01-16 A Monte Carlo Study for Photoneutron Dose Estimations around the High-Energy Linacs Mohammadi, N Miri-Hakimabad, S H Rafat-Motavalli, L J Biomed Phys Eng Original Article Background: High-energy linear accelerator (linac) is a valuable tool and the most commonly used device for external beam radiation treatments in cancer patients. In the linac head, high-energy photons with energies above the threshold of (γ,n) interaction produce photoneutrons. These photoneutrons deliver the extra dose to the patients undergoing radiation treatment and increase the risk of secondary cancer. Objective: In this study, a simplified model of the linac head was simulated and photoneutron dose equivalent was calculated at the isocenter and maze in the sphere detector. In addition, the absorbed and equivalent dose of photoneutron were estimated in the some organs of the phantom. Methods: The simulations were made using the Monte Carlo code. The ICRP reference adult male voxel phantom was used as the human body model for dosimetry calculations. Results: The results of dose calculations at the isocenter and maze showed that photoneutron dose decreases as the function of distance from the isocenter and increases with increasing the distance from the entrance maze. Conclusion: It is concluded that the simplified model of linac head is a useful and reliable method in dosimetry calculations. Calculations illustrated that the photoneutron dose is not negligible and duo to its harmful biological effects on body, it should be considered in the treatment plans. Shiraz University of Medical Sciences 2014-12-15 /pmc/articles/PMC4289520/ /pubmed/25599059 Text en © 2014: Journal of Biomedical Physics and Engineering This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported License (http://creativecommons.org/licenses/by-nc/3.0/deed.en_US), which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Mohammadi, N
Miri-Hakimabad, S H
Rafat-Motavalli, L
A Monte Carlo Study for Photoneutron Dose Estimations around the High-Energy Linacs
title A Monte Carlo Study for Photoneutron Dose Estimations around the High-Energy Linacs
title_full A Monte Carlo Study for Photoneutron Dose Estimations around the High-Energy Linacs
title_fullStr A Monte Carlo Study for Photoneutron Dose Estimations around the High-Energy Linacs
title_full_unstemmed A Monte Carlo Study for Photoneutron Dose Estimations around the High-Energy Linacs
title_short A Monte Carlo Study for Photoneutron Dose Estimations around the High-Energy Linacs
title_sort monte carlo study for photoneutron dose estimations around the high-energy linacs
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289520/
https://www.ncbi.nlm.nih.gov/pubmed/25599059
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