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Contribution of Intestinal Smooth Muscle to Crohn’s Disease Fibrogenesis

Mesenchymal cells transdifferentiation and extracellular matrix deposition are involved in the fibrotic process of Crohn’s disease (CD). Mesenchymal smooth muscle cells (SMCs) de-differentiation, driven by Platelet-derived growth factor (PDGF) that counteracts Transforming growth factor (TGF-β) has...

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Detalles Bibliográficos
Autores principales:	Severi, C., Sferra, R., Scirocco, A., Vetuschi, A., Pallotta, N., Pronio, A., Caronna, R., Di Rocco, G., Gaudio, E., Corazziari, E., Onori, P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PAGEPress Publications, Pavia, Italy 2014
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289851/ https://www.ncbi.nlm.nih.gov/pubmed/25578979 http://dx.doi.org/10.4081/ejh.2014.2457

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