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Variations in local calcium signaling in adjacent cardiac myocytes of the intact mouse heart detected with two-dimensional confocal microscopy
Dyssynchronous local Ca release within individual cardiac myocytes has been linked to cellular contractile dysfunction. Differences in Ca kinetics in adjacent cells may also provide a substrate for inefficient contraction and arrhythmias. In a new approach we quantify variation in local Ca transient...
Autores principales: | Hammer, Karin P., Hohendanner, Felix, Blatter, Lothar A., Pieske, Burkert M., Heinzel, Frank R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4290493/ https://www.ncbi.nlm.nih.gov/pubmed/25628569 http://dx.doi.org/10.3389/fphys.2014.00517 |
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