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Transient Global Amnesia Associated with a Unilateral Infarction of the Fornix: Case Report and Review of the Literature

Stroke is an extremely uncommon cause of transient global amnesia (TGA). Unilateral lesions of the fornix rarely cause amnesia and have not previously been reported to be associated with the distinctive amnesic picture of TGA. We describe the case of a 60-year-old woman who presented with acute onse...

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Autores principales: Gupta, Mihir, Kantor, Molly A., Tung, Christie E., Zhang, Niushen, Albers, Gregory W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4290584/
https://www.ncbi.nlm.nih.gov/pubmed/25628601
http://dx.doi.org/10.3389/fneur.2014.00291
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author Gupta, Mihir
Kantor, Molly A.
Tung, Christie E.
Zhang, Niushen
Albers, Gregory W.
author_facet Gupta, Mihir
Kantor, Molly A.
Tung, Christie E.
Zhang, Niushen
Albers, Gregory W.
author_sort Gupta, Mihir
collection PubMed
description Stroke is an extremely uncommon cause of transient global amnesia (TGA). Unilateral lesions of the fornix rarely cause amnesia and have not previously been reported to be associated with the distinctive amnesic picture of TGA. We describe the case of a 60-year-old woman who presented with acute onset, recent retrograde, and anterograde amnesia characteristic of TGA. Serial magnetic resonance imaging showed a persistent focal infarction of the body and left column of the fornix, without acute lesions in the hippocampus or other structures. Amnesia resolved in 6 h. Infarction of the fornix should thus be included in the differential diagnosis of TGA, as it changes the management of this otherwise self-limited syndrome.
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spelling pubmed-42905842015-01-27 Transient Global Amnesia Associated with a Unilateral Infarction of the Fornix: Case Report and Review of the Literature Gupta, Mihir Kantor, Molly A. Tung, Christie E. Zhang, Niushen Albers, Gregory W. Front Neurol Neuroscience Stroke is an extremely uncommon cause of transient global amnesia (TGA). Unilateral lesions of the fornix rarely cause amnesia and have not previously been reported to be associated with the distinctive amnesic picture of TGA. We describe the case of a 60-year-old woman who presented with acute onset, recent retrograde, and anterograde amnesia characteristic of TGA. Serial magnetic resonance imaging showed a persistent focal infarction of the body and left column of the fornix, without acute lesions in the hippocampus or other structures. Amnesia resolved in 6 h. Infarction of the fornix should thus be included in the differential diagnosis of TGA, as it changes the management of this otherwise self-limited syndrome. Frontiers Media S.A. 2015-01-12 /pmc/articles/PMC4290584/ /pubmed/25628601 http://dx.doi.org/10.3389/fneur.2014.00291 Text en Copyright © 2015 Gupta, Kantor, Tung, Zhang and Albers. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Gupta, Mihir
Kantor, Molly A.
Tung, Christie E.
Zhang, Niushen
Albers, Gregory W.
Transient Global Amnesia Associated with a Unilateral Infarction of the Fornix: Case Report and Review of the Literature
title Transient Global Amnesia Associated with a Unilateral Infarction of the Fornix: Case Report and Review of the Literature
title_full Transient Global Amnesia Associated with a Unilateral Infarction of the Fornix: Case Report and Review of the Literature
title_fullStr Transient Global Amnesia Associated with a Unilateral Infarction of the Fornix: Case Report and Review of the Literature
title_full_unstemmed Transient Global Amnesia Associated with a Unilateral Infarction of the Fornix: Case Report and Review of the Literature
title_short Transient Global Amnesia Associated with a Unilateral Infarction of the Fornix: Case Report and Review of the Literature
title_sort transient global amnesia associated with a unilateral infarction of the fornix: case report and review of the literature
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4290584/
https://www.ncbi.nlm.nih.gov/pubmed/25628601
http://dx.doi.org/10.3389/fneur.2014.00291
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