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Pathway analysis and transcriptomics improve protein identification by shotgun proteomics from samples comprising small number of cells - a benchmarking study
BACKGROUND: Proteomics research is enabled with the high-throughput technologies, but our ability to identify expressed proteome is limited in small samples. The coverage and consistency of proteome expression are critical problems in proteomics. Here, we propose pathway analysis and combination of...
Autores principales: | Sun, Jing, Zhang, Guang Lan, Li, Siyang, Ivanov, Alexander R, Fenyo, David, Lisacek, Frederique, Murthy, Shashi K, Karger, Barry L, Brusic, Vladimir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4290587/ https://www.ncbi.nlm.nih.gov/pubmed/25521637 http://dx.doi.org/10.1186/1471-2164-15-S9-S1 |
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