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Pathway analysis and transcriptomics improve protein identification by shotgun proteomics from samples comprising small number of cells - a benchmarking study

BACKGROUND: Proteomics research is enabled with the high-throughput technologies, but our ability to identify expressed proteome is limited in small samples. The coverage and consistency of proteome expression are critical problems in proteomics. Here, we propose pathway analysis and combination of...

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Detalles Bibliográficos
Autores principales: Sun, Jing, Zhang, Guang Lan, Li, Siyang, Ivanov, Alexander R, Fenyo, David, Lisacek, Frederique, Murthy, Shashi K, Karger, Barry L, Brusic, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4290587/
https://www.ncbi.nlm.nih.gov/pubmed/25521637
http://dx.doi.org/10.1186/1471-2164-15-S9-S1

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