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Localization and local translation of Arc/Arg3.1 mRNA at synapses: some observations and paradoxes

Arc is a unique immediate early gene whose expression is induced as synapses are being modified during learning. The uniqueness comes from the fact that newly synthesized Arc mRNA is rapidly transported throughout dendrites where it localizes near synapses that were recently activated. Here, we summ...

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Detalles Bibliográficos
Autores principales: Steward, Oswald, Farris, Shannon, Pirbhoy, Patricia S., Darnell, Jennifer, Driesche, Sarah J. Van
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4290588/
https://www.ncbi.nlm.nih.gov/pubmed/25628532
http://dx.doi.org/10.3389/fnmol.2014.00101